The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently conceptualized as being analogous to weather forecasting, however it has some key differences and remains a non-trivial task. The spread of diseases is subject to multiple confounding factors spanning human behavior, pathogen dynamics, weather and environmental conditions. Research interest has been fueled by the increased availability of rich data sources capturing previously unobservable facets and also due to initiatives from government public health and funding agencies. This has resulted, in particular, in a spate of work on 'data-centered' solutions which have shown potential in enhancing our forecasting capabilities by leveraging non-traditional data sources as well as recent innovations in AI and machine learning. This survey delves into various data-driven methodological and practical advancements and introduces a conceptual framework to navigate through them. First, we enumerate the large number of epidemiological datasets and novel data streams that are relevant to epidemic forecasting, capturing various factors like symptomatic online surveys, retail and commerce, mobility, genomics data and more. Next, we discuss methods and modeling paradigms focusing on the recent data-driven statistical and deep-learning based methods as well as on the novel class of hybrid models that combine domain knowledge of mechanistic models with the effectiveness and flexibility of statistical approaches. We also discuss experiences and challenges that arise in real-world deployment of these forecasting systems including decision-making informed by forecasts. Finally, we highlight some challenges and open problems found across the forecasting pipeline.

The accurate forecasting of infectious epidemic diseases such as influenza is a crucial task undertaken by medical institutions. Although numerous flu forecasting methods and models based mainly on historical flu activity data and online user-generated contents have been proposed in previous studies, no flu forecasting model targeting multiple countries using two types of data exists at present. Our paper leverages multi-task learning to tackle the challenge of building one flu forecasting model targeting multiple countries; each country as each task. Also, to develop the flu prediction model with higher performance, we solved two issues; finding suitable search queries, which are part of the user-generated contents, and how to leverage search queries efficiently in the model creation. For the first issue, we propose the transfer approaches from English to other languages. For the second issue, we propose a novel flu forecasting model that takes advantage of search queries using an attention mechanism and extend the model to a multi-task model for multiple countries' flu forecasts. Experiments on forecasting flu epidemics in five countries demonstrate that our model significantly improved the performance by leveraging the search queries and multi-task learning compared to the baselines.

With influenza cases elevated nationally and widespread throughout the country, researchers led by Boston Children's Hospital contend that machine learning can produce highly accurate local flu surveillance. In fact, they say that combining two forecasting methods with artificial intelligence produces the most accurate estimates of flu activity available to date--a week ahead of traditional healthcare-based reports, at the state level across the United States. While the Centers for Disease Control and Prevention monitors influenza-like illnesses (ILI) in the U.S. by gathering information from physicians' reports about patients with ILI seeking medical attention, the availability of the data has a lag time of as much as two weeks. However, in a study published on Friday in Nature Communications, researchers say they have successfully combined Google search frequencies and electronic health record data with spatio-temporal trends in influenza activity to produce forecasts with higher correlation and lower errors than all other tested models for current ILI activity at the state level. "We believe that the accuracy of our method involves a balance between responsiveness and robustness," state the authors.